Published research

                                       Cancer research:

 

Velasco G, Sanchez C, Guzman M (2016) Anticancer mechanisms of cannabinoids. Curr Oncol 23(2):S23–S32. doi:10.3747/co.23.3080PubMedPubMedCentralGoogle Scholar

 

Casanova ML, Blazquez C, Martinez-Palacio J, Villanueva C, Fernandez-Acenero MJ, Huffman JW, Jorcano JL, Guzman M (2003) Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. J Clin Invest 111(1):43–50. doi:10.1172/JCI16116PubMedPubMedCentralCrossRefGoogle Scholar

 

 

Carracedo A, Gironella M, Lorente M, Garcia S, Guzman M, Velasco G, Iovanna JL (2006) Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes. Cancer Res 66(13):6748–6755. doi:10.1158/0008-5472.CAN-06-0169PubMedCrossRefGoogle Scholar

 

Cianchi F, Papucci L, Schiavone N, Lulli M, Magnelli L, Vinci MC, Messerini L, Manera C, Ronconi E, Romagnani P, Donnini M, Perigli G, Trallori G, Tanganelli E, Capaccioli S, Masini E (2008) Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alpha – mediated ceramide De novo synthesis in colon cancer cells. Clin Cancer Res 14(23):7691–7700. doi:10.1158/1078-0432.CCR-08-0799PubMedCrossRefGoogle Scholar

 

De Petrocellis L, Melck D, Palmisano A, Bisogno T, Laezza C, Bifulco M, Di Marzo V (1998) The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. Proc Natl Acad Sci U S A 95(14):8375–8380PubMedPubMedCentralCrossRefGoogle Scholar

 

Galve-Roperh I, Sanchez C, Cortes ML, Gomez del Pulgar T, Izquierdo M, Guzman M (2000) Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat Med 6(3):313–319. doi:10.1038/73171PubMedCrossRefGoogle Scholar

 

Ligresti A, Moriello AS, Starowicz K, Matias I, Pisanti S, De Petrocellis L, Laezza C, Portella G, Bifulco M, Di Marzo V (2006) Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. J Pharmacol Exp Ther 318(3):1375–1387. doi:10.1124/jpet.106.105247  PubMedCrossRefGoogle Scholar

 

Shrivastava A, Kuzontkoski PM, Groopman JE, Prasad A (2011) Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy. Mol Cancer Ther 10(7):1161–1172. doi:10.1158/1535-7163.MCT-10-1100PubMedCrossRefGoogle Scholar

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