Published research

                                       Cancer research:


Velasco G, Sanchez C, Guzman M (2016) Anticancer mechanisms of cannabinoids. Curr Oncol 23(2):S23–S32. doi:10.3747/co.23.3080PubMedPubMedCentralGoogle Scholar


Casanova ML, Blazquez C, Martinez-Palacio J, Villanueva C, Fernandez-Acenero MJ, Huffman JW, Jorcano JL, Guzman M (2003) Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. J Clin Invest 111(1):43–50. doi:10.1172/JCI16116PubMedPubMedCentralCrossRefGoogle Scholar



Carracedo A, Gironella M, Lorente M, Garcia S, Guzman M, Velasco G, Iovanna JL (2006) Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes. Cancer Res 66(13):6748–6755. doi:10.1158/0008-5472.CAN-06-0169PubMedCrossRefGoogle Scholar


Cianchi F, Papucci L, Schiavone N, Lulli M, Magnelli L, Vinci MC, Messerini L, Manera C, Ronconi E, Romagnani P, Donnini M, Perigli G, Trallori G, Tanganelli E, Capaccioli S, Masini E (2008) Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alpha – mediated ceramide De novo synthesis in colon cancer cells. Clin Cancer Res 14(23):7691–7700. doi:10.1158/1078-0432.CCR-08-0799PubMedCrossRefGoogle Scholar


De Petrocellis L, Melck D, Palmisano A, Bisogno T, Laezza C, Bifulco M, Di Marzo V (1998) The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. Proc Natl Acad Sci U S A 95(14):8375–8380PubMedPubMedCentralCrossRefGoogle Scholar


Galve-Roperh I, Sanchez C, Cortes ML, Gomez del Pulgar T, Izquierdo M, Guzman M (2000) Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat Med 6(3):313–319. doi:10.1038/73171PubMedCrossRefGoogle Scholar


Ligresti A, Moriello AS, Starowicz K, Matias I, Pisanti S, De Petrocellis L, Laezza C, Portella G, Bifulco M, Di Marzo V (2006) Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. J Pharmacol Exp Ther 318(3):1375–1387. doi:10.1124/jpet.106.105247  PubMedCrossRefGoogle Scholar


Shrivastava A, Kuzontkoski PM, Groopman JE, Prasad A (2011) Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy. Mol Cancer Ther 10(7):1161–1172. doi:10.1158/1535-7163.MCT-10-1100PubMedCrossRefGoogle Scholar

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CBD oil is now looked upon as complimentary medicine. For most of us with chronic pain and ailments it is the best alternative for almost every symptom. Please note: We are not making any claims that CBD can or will improve your health, we are simply providing you with the research that is public information to make an informed decision yourself.+

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